ALZET CATHETERS

Via a catheter, ALZET® Osmotic Pumps can deliver substances into vessels, spinal cord, cerebral ventricles and brain parenchyma, and other organs or tissues. DURECT Corporation offers a range of specialized catheters, compatible with ALZET pumps, to enable targeted delivery to a variety of sites. ALZET pumps can be attached to catheter tubing with I.D ranging from 0.58 mm to 0.76 mm (0.023"-0.030").

Medical grade PE and Vinyl tubing, the most common catheter types used in laboratory animal research, are available sterile, individually packaged, and ready to use

Features

Sterile

Medical grade

Pre-cut to 15 cm lengths

Individually packaged

Ready to use

Fit all pump models

Catheter Applications with ALZET Osmotic Pumps

Direct delivery of test agents into any target tissue or organ

Delay delivery of test agents to allow for a surgical recovery period

Infuse for a shorter period using a longer duration pump

Infuse a smaller volume of solution

Create a time-patterned delivery of an agent

Rat Jugular Catheter

Catheter Material: Silicone

Specifications:

15.24 cm (6") of silicone catheter (0.94 OD; 0.51 mm ID) with a silicone suture patch and ALZET connection (1.19 mm OD; 0.61 mm ID). (Internal catheter volume is ~32-36 ul).

Optimum Animal Size:

250+ grams (for < 250 gram rats, cut tip to size for proper placement)

Features & Benefits:

Silicone patch facilitates anchoring to tissue

Silicone material is very flexible and less traumatic to vessels

Bevel tip if desired for easier insertion into vessels

ETO sterilized

Rat Femoral Catheter

Catheter Material: Polyurethane (PU)

Specifications:

20.32 cm (8") of Polyurethane catheter (1.02 mm OD; 0.61 mm ID); designed for intravenous cannulation. (Internal catheter volume is ~59 ul).

Optimum Animal Size:

Up to 300+ grams (for <175 gram rats, cut tip to size for proper placement)

Features & Benefits:

Retention beads at 3.81, 5.08, and 7.62 cm from the tip facilitate anchoring to tissue

Medical grade polyurethane softens at body temperature

Fits directly to pump (no step-up needed)

Rat Femoral Catheter (Tapered)

Catheter Material: Opaque Polyurethane

Specifications:

20.32 cm (8") of tapered radio-opaque polyurethane (1.40 mm to 0.99 mm OD; 0.61 mm constant ID); designed for intravenous cannulation. (Internal catheter volume is ~59 ul).

Optimum Animal Size:

Up to 300+ grams (for <175 gram rats, cut tip to size for proper placement)

Features & Benefits:

Retention beads at 3.81, 5.08, and 7.62 cm from the tip facilitate anchoring to tissue

Medical grade, tapered polyurethane minimizes kinking

Radio-opaque material and smooth surface minimize clotting

Lumen maintains consistent ID, so that the catheter can be shortened without compromising its tight fit onto pump

Rat Intrathecal Catheter

Catheter Material: Polyurethane (PU)

Specifications:

10 cm of 28G PU (0.36 mm OD; 0.18 mm ID) connected to 12.7 cm PU (0.84 mm OD; 0.36 mm ID) and ALZET connection (1.02 mm OD; 0.61 mm ID) with Teflon coated stylet wire. Total catheter length is 23.7 cm (9.33").

(Internal catheter volume is ~20 ul).

Optimum Animal Size:

Up to 300+ grams (cut distal end to desired length for proper placement)

Features & Benefits:

Designed for occipital insertion

Includes a Teflon coated stylet for easier placement

Protected tubing junction minimizes kinking at exit point from intrathecal space

Rat Intrathecal Catheter (Short)

Catheter Material: Polyurethane (PU)

Specifications:

10 cm of 28G PU (0.36 mm OD; 0.18 mm ID) connected to 4.0 cm PU (0.84 mm OD; 0.36 mm ID) and ALZET connection (1.02 mm OD; 0.61 mm ID) with Teflon coated stylet wire. Total catheter length is 15.0 cm (5.90"). (Internal catheter volume is ~10-11 ul).

Optimum Animal Size:

Up to 300+ grams (cut distal end to desired length for proper placement)

Features & Benefits:

Shorter length for lumbar insertion

Includes a Teflon coated stylet for easier placement

Protected tubing junction minimizes kinking at exit point from intrathecal space

Rat Intraperitoneal Catheter

Catheter Material: Polyurethane (PU)

Specifications:

13mm of 28G PU (0.36 mm OD; 0.18 mm ID) connected to 63.5 mm PU (0.84 mm OD; 0.36 mm ID) and ALZET connection (1.02 mm OD; 0.61 mm ID). Total catheter length is 8.8 cm (3.46"). (Internal catheter volume is ~10 ul).

Optimum Animal Size:

30+ grams (insertion marks for adaptation to smaller animals)

Features & Benefits:

Retention beads at 13 and 38 mm from the tip facilitate anchoring to tissue

Catheter tip optimum for use with other small vessels (e.g., femoral, carotid, etc.)

Marked at 9 and 11 mm to simplify adaptation for < 25 and 25-30 gram animals respectively

Mouse Jugular Catheter

Catheter Material: Polyurethane (PU)

Specifications:

13mm of 28G PU (0.36 mm OD; 0.18 mm ID) connected to 63.5 mm PU (0.84 mm OD; 0.36 mm ID) and ALZET connection (1.02 mm OD; 0.61 mm ID). Total catheter length is 8.8 cm (3.46"). (Internal catheter volume is ~10 ul).

Optimum Animal Size:

30+ grams (insertion marks for adaptation to smaller animals)

Features & Benefits:

Retention beads at 13 and 38 mm from the tip facilitate anchoring to tissue

Catheter tip optimum for use with other small vessels (e.g., femoral, carotid, etc.)

Marked at 9 and 11 mm to simplify adaptation for < 25 and 25-30 gram animals respectively

Mouse Jugular Catheter (Adjustable Length)

Catheter Material: Polyurethane (PU)

Specifications:

13mm of 28G PU (0.36 mm OD; 0.18 mm ID) connected to 25.4 mm PU (0.84 mm OD; 0.36 mm ID) connected to a 50 mm ALZET connection (1.02 mm OD; 0.61 mm ID). Total catheter length is 8.8 cm (3.46"). (Internal catheter volume is ~18 ul).

Optimum Animal Size:

30+ grams (insertion marks for adaptation to smaller animals)

Features & Benefits:

ALZET connection can be trimmed to achieve smaller lengths

Catheter tip optimum for use with other small vessels (e.g., femoral, carotid, etc.)

Retention beads at 13 and 35 mm from the tip facilitate anchoring to tissue

Marked at 9 and 11 mm to simplify adaptation for < 25 and 25-30 gram animals respectively

Mouse Jugular Catheter (Adjustable Length-Large Tip)

Catheter Material: Polyurethane (PU)

Specifications:

44.5 mm of 20G PU (0.84 mm OD; 0.36 mm ID) connected to a 50 mm ALZET connection (1.02 mm OD; 0.61 mm ID). Total catheter length is 9.5 cm (3.74"). (Internal catheter volume is ~20 ul).

Optimum Animal Size:

30+ grams (insertion marks for adaptation to smaller animals)

Features & Benefits:

ALZET connection can be trimmed to achieve smaller lengths

Catheter tip optimum for jugular cannulation

Retention beads at 13 and 35 mm from the tip facilitate anchoring to tissue

Marked at 9 and 11 mm to simplify adaptation for < 25 and 25-30 gram animals respectively

Mouse Intrathecal Catheter

Order No.: 0007743

Catheter Material: Polyurethane

Specifications:

2.5 cm 32G (0.23 mm OD; 0.09 mm ID) connected to 1 cm (0.76 mm OD; 0.38 mm ID), connected to a 2.5 cm (1.02 mm OD; 0.61 mm ID) ALZET connection with Teflon coated stylet wire. Total catheter length is 6cm (2.36"). (Internal catheter volume is ~8.6 ul).

Optimum Animal Size:

Adult mouse

Features & Benefits:

Distal end can be trimmed

Includes a Teflon coated stylet for easier placement

Catheter is provided sterile

Mouse Intraperitoneal Catheter

Catheter Material: Silicone and Polyurethane (PU)

Specifications:

3.0 cm of Silicone (0.94 mm OD; 0.51 mm ID) connected to 3.0 cm PU (1.02 mm OD; 0.61 mm ID). Fenestrations over first 1.0 cm Silicone tip. Total catheter length is 6.0 cm. (Internal catheter volume is ~15 ul).

Applications:

Peritoneal/Gastric delivery

Peritoneal delivery via subcutaneous pump

Easier pump replacement

Use larger pump for IP delivery in mice

Features & Benefits:

Fenestrations over Silicone tip for greater drug distribution

Movable suture bead for optimum adjustment of inserted catheter section

Flexible Silicone section minimizes tissue trauma

Polyethylene section provides optimum fit to all ALZET pump models; can be cut to desired length

Stress relief catheter junction prevents kinking and improves patency

ALZET CATHETERS

Medical grade PE and Vinyl tubing, the most common catheter types used in laboratory animal research, are available sterile, individually packaged, and ready to use

Catheter Applications with ALZET Osmotic Pumps

Rat Jugular Catheter

Catheter Material: Silicone

Specifications:

15.24 cm (6") of silicone catheter (0.94 OD; 0.51 mm ID) with a silicone suture patch and ALZET connection (1.19 mm OD; 0.61 mm ID). (Internal catheter volume is ~32-36 ul).

Optimum Animal Size:

250+ grams (for < 250 gram rats, cut tip to size for proper placement)

Features & Benefits:

Rat Femoral Catheter

Catheter Material: Polyurethane (PU)

Specifications:

20.32 cm (8") of Polyurethane catheter (1.02 mm OD; 0.61 mm ID); designed for intravenous cannulation. (Internal catheter volume is ~59 ul).

Optimum Animal Size:

Up to 300+ grams (for <175 gram rats, cut tip to size for proper placement)

Features & Benefits:

Rat Femoral Catheter (Tapered)

Catheter Material: Opaque Polyurethane

Specifications:

20.32 cm (8") of tapered radio-opaque polyurethane (1.40 mm to 0.99 mm OD; 0.61 mm constant ID); designed for intravenous cannulation. (Internal catheter volume is ~59 ul).

Optimum Animal Size:

Up to 300+ grams (for <175 gram rats, cut tip to size for proper placement)

Features & Benefits:

Catheter Material: Polyurethane (PU)

Specifications:

10 cm of 28G PU (0.36 mm OD; 0.18 mm ID) connected to 12.7 cm PU (0.84 mm OD; 0.36 mm ID) and ALZET connection (1.02 mm OD; 0.61 mm ID) with Teflon coated stylet wire. Total catheter length is 23.7 cm (9.33").

(Internal catheter volume is ~20 ul).

Optimum Animal Size:

Up to 300+ grams (cut distal end to desired length for proper placement)

Features & Benefits:

Rat Intrathecal Catheter (Short)

Catheter Material: Polyurethane (PU)

Specifications:

10 cm of 28G PU (0.36 mm OD; 0.18 mm ID) connected to 4.0 cm PU (0.84 mm OD; 0.36 mm ID) and ALZET connection (1.02 mm OD; 0.61 mm ID) with Teflon coated stylet wire. Total catheter length is 15.0 cm (5.90"). (Internal catheter volume is ~10-11 ul).

Optimum Animal Size:

Up to 300+ grams (cut distal end to desired length for proper placement)

Features & Benefits:

Catheter Material: Polyurethane (PU)

Specifications:

13mm of 28G PU (0.36 mm OD; 0.18 mm ID) connected to 63.5 mm PU (0.84 mm OD; 0.36 mm ID) and ALZET connection (1.02 mm OD; 0.61 mm ID). Total catheter length is 8.8 cm (3.46"). (Internal catheter volume is ~10 ul).

Optimum Animal Size:

30+ grams (insertion marks for adaptation to smaller animals)

Features & Benefits:

Mouse Jugular Catheter

Catheter Material: Polyurethane (PU)

Specifications:

13mm of 28G PU (0.36 mm OD; 0.18 mm ID) connected to 63.5 mm PU (0.84 mm OD; 0.36 mm ID) and ALZET connection (1.02 mm OD; 0.61 mm ID). Total catheter length is 8.8 cm (3.46"). (Internal catheter volume is ~10 ul).

Optimum Animal Size:

30+ grams (insertion marks for adaptation to smaller animals)

Features & Benefits:

Catheter Material: Polyurethane (PU)

Specifications:

13mm of 28G PU (0.36 mm OD; 0.18 mm ID) connected to 25.4 mm PU (0.84 mm OD; 0.36 mm ID) connected to a 50 mm ALZET connection (1.02 mm OD; 0.61 mm ID). Total catheter length is 8.8 cm (3.46"). (Internal catheter volume is ~18 ul).

Optimum Animal Size:

30+ grams (insertion marks for adaptation to smaller animals)

Features & Benefits:

Mouse Jugular Catheter (Adjustable Length-Large Tip)

Catheter Material: Polyurethane (PU)

Specifications:

44.5 mm of 20G PU (0.84 mm OD; 0.36 mm ID) connected to a 50 mm ALZET connection (1.02 mm OD; 0.61 mm ID). Total catheter length is 9.5 cm (3.74"). (Internal catheter volume is ~20 ul).

Optimum Animal Size:

30+ grams (insertion marks for adaptation to smaller animals)

Features & Benefits:

Order No.: 0007743

Catheter Material: Polyurethane

Specifications:

2.5 cm 32G (0.23 mm OD; 0.09 mm ID) connected to 1 cm (0.76 mm OD; 0.38 mm ID), connected to a 2.5 cm (1.02 mm OD; 0.61 mm ID) ALZET connection with Teflon coated stylet wire. Total catheter length is 6cm (2.36"). (Internal catheter volume is ~8.6 ul).

Optimum Animal Size:

Adult mouse

Features & Benefits:

Mouse Intraperitoneal Catheter

Catheter Material: Silicone and Polyurethane (PU)

Specifications:

3.0 cm of Silicone (0.94 mm OD; 0.51 mm ID) connected to 3.0 cm PU (1.02 mm OD; 0.61 mm ID). Fenestrations over first 1.0 cm Silicone tip. Total catheter length is 6.0 cm. (Internal catheter volume is ~15 ul).

Applications:

Features & Benefits:

*All specialized catheters are supplied sterile (ETO sterilized)